Your diagnosis

Mutations and other DNA changes in NSCLC

Alterations 

Some people with NSCLC have a change in their DNA that causes their cancer to start growing. These changes can include things like ‘mutations’ (where a small bit of the DNA changes) and ‘fusions’ of different parts of your DNA (where two different pieces of DNA stick together incorrectly). These changes are given names based on what part of the DNA they happen in. Some examples of this are ALK+, RET+, and ROS1+ NSCLC.

Click on one of the options below to learn more about these types of NSCLC, including who they typically affect and what having one of these types of NSCLC might mean for you.


ALK
Anaplastic lymphoma kinase
DNA
Deoxyribonucleic acid
NSCLC
Non-small cell lung cancer
RET
Rearranged during transfection
ROS1+
C-ros oncogene 1